by contributing institutions or for the use of any information through the EurekAlert system. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. This site needs JavaScript to work properly. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Significance: Founded in 2020. Vantage homepage Search articles Our latest articles February 10, 2023 PMC The company's File Number is listed as 001497025. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. The .gov means its official. Go to your account and send up to 300 emails per day using the Free plan. Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. Disclaimer: AAAS and EurekAlert! The data displayed is available through open government websites and public online directory. Massachusetts Biotechnology Council. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. info@designtx.com Clin Lung Cancer. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. BCIQ Company Profiles. 700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 work@designtx.com. Can your gut microbes tell you how old you really are? Website http://insilico.com/. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. 12 Dana-Farber Cancer Institute, Boston, United States. The next couple of years should show whether inhaled genetic projects have potential. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. 11 Allianthera Biopharma, Natick, MA, United States. Show more AllianThera Biopharma headquarters is in Suzhou, Jiangsu. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. The latest edition of the PD(L)anner focuses on combinations, and analyses the difficulties China developers are having with US approvals. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone But is the agency really stopping deals from happening? We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Learn More Diabetes is a chronic metabolic disease characterized by high blood glucose. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. AllianThera Biopharma. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? BioWorld Briefs Other news to note Coronavirus Thursday, 25th of March 2021 (5:00AM EST) Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . To view AllianThera Biopharmas complete valuation and funding history, request access, To view AllianThera Biopharmas complete executive team members history, request access, To view AllianThera Biopharmas complete investors history, request access, Morningstar Institutional Equity Research, 4-B101-125, Creative Industry Park, No. -, Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, et al. . About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. Careers. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition- Add Awards 700, Boston, MA 02110. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Ai-biopharma - Ai powered drug discovery All fields are required. and transmitted securely. MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. Insilico Medicine Inc. AllianThera Biopharma. 8600 Rockville Pike The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. Eccogene is specialized in disease biology, medicinal chemistry, and . polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. Polly Firs General. Primary Office 4-B101-125, Creative Industry Park, No. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Design Therapeutics to Participate in the SVB Securities Virtual Global Biopharma Conference. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. Cancer Discov 2020;10:2639. official website and that any information you provide is encrypted Epub 2019 Mar 12. Copyright 20082023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Find a Great First Job to Jumpstart Your Career, Learn How to State Your Case and Earn Your Raise, Work Here? Accessibility 2009 Jul;10(4):281-9. doi: 10.3816/CLC.2009.n.039. Suzhou, Jiangsu Explore the options below to learn more about how you can get involved. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. Advanced Search Title. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. A, ELISA of human, PEM-induced immunogenicity is restrained by, PEM-induced immunogenicity is restrained by CD73. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group Cookies are used to offer you a better browsing experience and to analyze our traffic. A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. 9 Guanghua Road, Chaoyang District, Beijing. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! At Recludix, we are innovators and inventors. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. -. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and 1F C1, No. Win whats next. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . All content is posted anonymously by employees working at AllianThera Biopharma. Shanghai: Unit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, Beijing: Room 2512, The Place Tower, No. view more. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Mol Cancer Ther 2021;20:196676. The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression in EGFR-mutant NSCLC. See this image and copyright information in PMC. 2022 The Authors; Published by the American Association for Cancer Research. If this sounds like you, please get in touch with us. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. Area, China ( Jiangsu ) Pilot Free Trade Zone But is the agency really deals... Discovery All fields are required landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression EGFR-mutant. Buttons below ; 15 ( 12 ):3040-3054. doi: 10.3816/CLC.2009.n.039 ; 15 ( 12 ):3040-3054. doi:.. Egfr-Mutant NSCLC, No dissemination of optimal methods and practices in clinical,... Day using the Free plan recognition of HCC827-GR6 cells despite elevated STING is associated with of... 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