Long-circulating vectors for the systemic delivery of genes. The level of genetic conservation between human and macaques has yet to be fully investigated, but the results from this study will be useful for all biomedical research. Its natural to have double-dealing personality? Only with intervention would this happen. Type AB An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes. So what does this mean? This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). They are often self-focused and may come off as selfish, but they simply need to know how to best take care of themselves. Yuan Q., Zhou Z., Lindell S., Higley J., Ferguson B., Thompson R., Lopez J., Suomi S., Baghal B., Baker M., Mash D., Barr C., Goldman D. The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human. The first human was a result of scientific research combining primates with the gods genes. Mountain biking in San Antonio, Texas, is made so much more fun because of the Monkey Loop. The probe distribution across the Chinese rhesus macaque and human chromosomes is shown in Table1 and the conserved synteny is illustrated in Fig. The study: Thousands of customers of 23andMe, a genotyping company, submitted saliva samples for DNA analysis and answered questionnaires about their racial and ethnic identifications. 2002 Sep;43(9):3075-80. Though the majority of the human markers were mapped to the rhesus macaque chromosome orthologs that Rogers et al. The last common ancestor of humans and macaques is estimated to have lived approximately 25million years ago [1]. For more than 40 years Grease Monkey has been the oil change expert and one-stop shop for your automotive And no new grain has since been developed. The languages in neighboring countries in Europe show no resemblance to the Basque language, so this has become a real mystery to the linguist. There are very few aberrations. But, 23andMe codes for genes that are pretty well-established in tracing ancestry, according to a company representative. Heute, nach behutsamer und grndlicherRenovierung knnen wir auch Ihnen einbreites Spektrum an reprsentativen Rumlichkeitenfr Ihre auergewhnliche Veranstaltung sei es Hochzeit, Seminar oderEmpfang anbieten. It would appear that Victoria is actually a direct descendant of Ferdinand of Castille, who retook he city of Castille in 1236, where the surgeon Abulcasis had counseled King Hakam II about a family whos sons died easily. For comparisons between the two macaques, Chinese rhesus macaque (rheMac3) positions were converted from Indian rhesus macaque (rheMac2) positions using LiftOver [46] instead of directly from human (hg19) so converted regions could be tracked between the genome builds. Thats why we cover our services and products for either three months or 3,000 miles, whichever comes first. They collectively hailed from 48 states. and Nick Lerche, CNPRC (No. However, mules are born sterile because there is no genetic relationship between the horse and the donkey. Kanthaswamy S., Gill L., Satkoski J., Goyal V., Malladi V., Kou A., Basuta K., Sarkisyan L., George D., Smith D.G. Tought by the creator and send them to teach humans. Then you begin to wonder just where a supposed blue blood like Victoria got her Arab Royalty Disease??? Yes we all do have our intuition we must listen to God voice in our heart and mind and follow his guidance The .gov means its official. All of the basic grains that humans rely on for food have been determined to have all appeared at the same time spanning roughly a 10,000 year period. The 3' UTRs of selenoprotein They knew about aviation, metallurgy, the universe, the cosmic progression, medicine and evidently genetics. Lacerations and scrapes are usually gone in 4-5 days. People with type B blood tend to be the creators, the actors, the writers, and the poets. Federal government websites often end in .gov or .mil. Feel free to call a store with questions about services for your year/make/model. 2020 Jan 10;11:373. doi: 10.3389/fnagi.2019.00373. Its said that the predominant blood type in Japan is A, with about 40% of the population, while Americans tend toward O, about 37%. Whether you have a fleet of 3 or 3,000, we are ready to get your drivers taken care of fast and back on the road. Single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) are highly variable in the human population and are often associated with human diseases and other phenotypes [9], [18], [19], [20], [21], [22]. Since only two rhesus macaques were genotyped, the number of copy number regions and doubled regions was probably underestimated. Phone: 713-798-6539 | Fax: 713-798-5741 [35] who used the orthologous SNPs from Kanthaswamy et al. The BCM-HGSC is currently sequencing more than 100 rhesus macaques from several different NIH-funded research colonies in order to identify and characterize genetic variation in this species.. would love to know where i come from since i have always felt like i just dont belong here. Front Med Technol. So lets start. After the freeze ended this hybrid race traveled up into the British Isles and settled there. amir johnson shooting; lasalle hotel seattle. To keep this in perspective, only about 5% of all royalty have Rh-Factor negative bloodwhich means less than the general population. Is the introduction of Caucasian related to the RH-blood factor. Could they have come here and manipulated life forms already present on earth to create modern man? The macaque biomedical model has been instrumental in studying and combating infectious, cardiovascular, metabolic, and respiratory diseases, as well as understanding reproduction, development, aging, and neuroscience in humans [2], [3], [4], [5], [6], [7], [8]. Res. Red or reddish hair. Mapped probe locations and gene annotations for the Indian rhesus macaque and human comparison. Supplementary File 4 All copy number region locations, gene annotations, and copy number calls for all comparisons. Chromosomal rearrangements, such as the fusion of rhesus macaque chromosomes 12 and 13 that are orthologous to human chromosome 2, were in agreement with previous observations in great apes [26], baboons [27], and Japanese macaques [28]. The NHGRI Division of Extramural Research supports grants for research and for training and career development at sites nationwide. Use of primates in research: a global overview. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. The Basques very likely had a large portion of people with red hair green eyes as a result of inbreeding. Example of identified genes with their disease associations. regular price. Some of them work hard for NPO activities or other volunteering. If the RH-negative factor is a normal presentation of blood, then why is there a problem when a mother of the RH-negative blood group gives birth to an RH-positive blood group baby. Grease Monkey Store Locations in Cibolo, TX. This would lend credence that the RH-negative factor was introduced from an outside source. Raw and smoothed copy number estimation were both conducted using the R package aroma.affymetrix, version 2.10.1 [45]. 8600 Rockville Pike about navigating our updated article layout. 2001 Oct 23;98(22):12754-9. doi: 10.1073/pnas.221450098. Andi, which stands for inserted DNA spelled backwards, was born at Oregon Regional Primate Research Center at Oregon Health Sciences University. Whether you have a fleet of 3 or 3,000, we are ready to get your drivers taken care A working group was convened to coordinate evaluation and comparison of each assembly and guide melding into a single assembly. Personality match the chart hehe am Type A Lower body temperature. As we know from the history, Zahra competed in grandeur and magnificence with Baghdad. You are a sensitive person. Independent assemblies of the rhesus genome data were carried out at each of the three sequencing centers using different and complementary approaches and then combined into a single "melded assembly." Greetings from Calgary, thank you for reading and sharing your story in our blog. Was there a cross-breeding of two human like beings, similar but genetically different? Though rhesus macaques are one of the closest model organisms to humans, the available genetic data repositories are not as extensive or nearly as detailed as other more distantly related model organisms such as mice or yeast. Observed genetic rearrangement of rhesus macaque (R) chromosome 10 as compared to orthologous human (H) chromosomes 20 and 22 for (a) Indian rhesus macaque and human, (b) Chinese rhesus macaque and human, and (c) between the Indian and Chinese rhesus macaques. Three proto types of humans were created. Proc Natl Acad Sci U S A. They obviously had advanced technology capable of space travel and air travel. ( Read my articles here in linkedinThe watchers.). Zhang X., Goodsell J., Norgren R. Limitations of the rhesus macaque draft genome assembly and annotation. Introduction. sharing sensitive information, make sure youre on a federal The Macaque Genome Sequencing Consortium is led by the Baylor College of Medicine Human Genome Sequencing Center, and in collaboration with the J. Craig Venter Institute Joint Technology Center, and the Genome Sequencing Center at Washington University, St. Louis. The rhesus macaque is an Old World monkey. The RH factor is the Rhesus (rhesus as in monkey) blood factor. Valid only at address listed. Here is a brief list of the most common. This assembly, released in Feb 2006, was used for gene predictions, and ongoing analysis. Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing. From the 205,532 markers that mapped to both Indian and Chinese rhesus macaques, 22,385 markers mapped to 3709 unique accession numbers and 3682 genes in Indian rhesus macaque, and 22,101 markers mapped to 3675 accession numbers and 3650 genes in Chinese rhesus macaque. This means that important features that have been conserved in primates over time can be more easily seen by comparing rhesus to human, than chimp to human. The chromosomal distribution of the markers across both human and Indian rhesus macaque genomes is summarized in Table1 and the generalized synteny of Indian rhesus macaque chromosomal segments relative to human chromosomes is shown in Fig. As part of our top-notch service, our certified technicians perform a thorough 16-point inspection with every oil change. They are calm about themselves, and have ability to judge things objectively. The comparison between the two rhesus macaques resulted in 205,532 markers that mapped to the genomes of both rhesus macaques and 1146 makers that mapped to multiple locations. This primate model organism, while Discount off regular price. As you get closer to them, it will become a way of communication to understand each other. The study included 150,000 white participants and several thousand Latinos and African-Americans. Kumar S., Hedges S.B. I have done it Coffman R.L., Hessel E.M. Nonhuman primate models of asthma. Heritability of social behavioral phenotypes and preliminary associations with autism spectrum disorder risk genes in rhesus macaques: A whole exome sequencing study. These discrepancies may be due to the gene being absent in rhesus macaques or not mapping to a copy number region complimentary to the probes used in rhesus macaques. More sensitive vision and other senses. All markers with their mapped annotated genes for all comparisons are summarized in Table2 and listed in detail for the Indian rhesus-human, Chinese rhesus-human, and ChineseIndian rhesus comparisons in Supplementary File 1, Supplementary File 2, Supplementary File 3, respectively. Rhesus monkeys are used for essential research in neuroscience, behavioral biology, infectious diseases, reproductive physiology, endocrinology, cardiovascular studies, pharmacology and other areas. BCM-HGSC and Wash U each sequenced 2.5x WGS and JCVI 1x. o Worst Traits: Critical, indecisive, unforgiving, two-faced, aloof, and split personality. However, rhesus macaques carry three times the genetic diversity observed in humans [16], and large scale genomic rearrangements have also been observed between these two species [17], circumstances that may either limit or enhance the suitability of the rhesus macaque model. In a genome comparison of the two regional populations of rhesus macaques, Yan et al. Best traits: Agreeable, optimistic Void where permitted. Mem Inst Oswaldo Cruz. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. The present studies examine the extent to which either beta-galactosidase or luciferase expression plasmids are targeted to the retina in the adult rhesus monkey following This interbreeding for the most part created no problems in the resulting offspring, except for a line that inherited, from their godly parents, the RH-negative blood type. Intravenous, non-viral RNAi gene therapy of brain cancer. PMC and transmitted securely. Since CNVs are highly variable and have been linked to some phenotypes, including some diseases, in humans, analyses similar to those done with the SNPs can be used to identify conserved CNVs. The egg was then fertilized with sperm from a normal male monkey. These gene families include important immune related genes, as well as genes with functions not yet fully known. Fructose-fed rhesus monkeys: a nonhuman primate model of insulin resistance, metabolic syndrome, and type 2 diabetes. Is the blood group alien? An official website of the United States government. Each one successively more advanced. They often ask for wishes and ideals in detail to their partners, without thinking. Aging in rhesus monkeys: relevance to human health interventions. Oklahoma, the study revealed, has the highest proportion of self-identified African-Americans with Native American genes. And yet this doesnt mean they have little emotion, they are emotional enough to cry with movies without hesitation. 85% of humans have the monkey gene (RH+) and 15% do not (RH-) .RH- people are characterized by higher IQs, sensitive vision, lower body temperatures, sensitivity to heat and sunlight, psychic power, ability to stop watches and electrical appliances and having extra vertebrae. Bolded numbers indicate probes in orthologous chromosomes. Kanthaswamy et al. Taxes and/or disposal fees extra, where permitted. Gonzalez E., Kulkarni H., Bolivar H., Mangano A., Sanchez R., Catano G., Nibbs R.J., Freedman B.I., Quinones M.P., Bamshad M.J., Murthy K.K., Rovin B.H., Bradley W., Clark R.A., Anderson S.A., O'Connell R.J., Agan B.K., Ahuja S.S., Bologna R., Sen L., Dolan M.J., Ahuja S.K. R Foundation for Statistical Computing; Vienna, Austria: 2012. Roth G.S., Mattison J.A., Ottinger M.A., Chachich M.E., Lane M.A., Ingram D.K. 1a. administration. Install New Oil Filter;16-Point Inspection & Service;Clean Exterior Glass; Requires leadlight restoration purchase at, mixture of new coolant / antifreeze fluid. Copy number comparison between Indian rhesus macaque and human identified 1679 copy number regions with 206 regions that had copy number differences greater than or less than a factor of two (doubled regions). "Many Americans claim ancestry they don't have or don't claim ancestry that they do," said Saunt. However they are just acting as they are, and if you get close to them you will understand. Even before DNA analysis, families repudiated relatives they knew were theirs. 2022 Jun 16;14(6):1283. doi: 10.3390/pharmaceutics14061283. For example, human chromosome 2 corresponds to rhesus macaque chromosomes 12 and 13. The Bible says, and the falling angels looked upon woman and found her pleasant to behold and took her as their wives. The study is not without controversy: Personal genotyping companies like 23andMe have come under fire for cherry-picking the genes they analyze (millions out of billions) for participants' DNA profiles. RR000169-48), by an ARRA supplement awarded to S.K. to put them on file because they want to ask them later for blood donation as it is most rare and can save lives, you CAN DO A DNA test Arabic scholars who discovered many blood disease and inventor of surgical toolswas Abul Qasim Khalaf ibn al-Abbas al-Zahravi. Anim. facebook.com/hochzeitsschlosshollenburg/. They are inhibited and timid, but have wide range of interests. The https:// ensures that you are connecting to the The Mystery of Rh-Negative Blood ,Genetic Origin Unknown! Epub 2001 Oct 9. National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, U.S. Department of Health and Human Services, U.S. Department of Health & Human Services, NIH Institute and Center Contact Information. ", A cousin of the Black Lives Matter founder died after being repeatedly tased by the LAPD, White women on TikTok are making DNA binders in case they get murdered, By subscribing to this BDG newsletter, you agree to our. * So whatever your automotive maintenance or repair needs, come see the Grease Monkey difference. Widespread expression of an exogenous gene in the eye after intravenous administration. The site is secure. Apparently, Queen Victoria was a carrier of Hemophilia and gave it to all of her children who then intermarried and infected the bloodlines of very throne in Europe during the 1800s and 1900s. Thank you. *Limited Warranty. Any research regarding the immune system? Wir laden Sie ein, Ihre Ansprche in unserem Haus mit drei(miteinander kombinierbaren) Szenerien vielseitig auszudrcken:Klassisch, Modern und Zeremoniell. 2004 Aug;6(8):906-12. doi: 10.1002/jgm.575. They correspond completely different depend on situation, so some people might get confused. They make wonderful leaders, have great intuition, and manage stress incredibly well. I just got a pretty good cut on Saturday and the scabs are already falling off (3 days later). They really are very innocent and timid. The sequencing of the rhesus genome was conducted at the Baylor College of Medicine Human Genome Sequencing Center in Houston, the Genome Sequencing Center at Washington University School of Medicine in St. Louis and the J. Craig Venter Institute in Rockville, Md., which are part of the NHGRI-supported Large-Scale Sequencing Research Network. They knew about atomic energy and weapons and used them. "For a generation, historians have been writing books about how race is culturally constructed," said Claudio Saunt, a University of Georgia historian, commenting on the study. The doubled regions for the Chinese rhesus-human comparison mapped to 308 unique RefSeq accession numbers and 154 unique genes in human and 26 unique accession numbers and genes in Chinese rhesus macaque. +43 2739 2229 This was displayed on the UCSC browser in April 2005. This project specifically targets mammalian Y chromosomes for additional sequencing and sequence finishing. Genomic resources for rhesus macaques (Macaca mulatta). The project was a 5x WGS draft assembly with additional finished regions (up to 500 Mb) and an undefined BAC component, as needed to ensure overall quality. If youre AB, you can take any blood. I hope to hear from u soon , as Soon as possible actually. As much as 12% of self-described European Americans from South Carolina and Louisiana had African ancestry. will also be available for a limited time. Since the two groups had different blood-types, the army doctors simply claimed that it was their blood-types making them rebel, rather than accept that just maybe, most people dont like having their country invaded. The UCSC Table Browser data retrieval tool. In its paper, the Rhesus Macaque Genome Sequence and Analysis Consortium, supported in part by the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), compared the genome sequences of rhesus macaque (Macaca mulatta) with that For example, researchers found white people with African ancestry at much higher rates in southern states. Schloss Hollenburg liegt idyllisch zwischen Weinbergen und der Donau mitten im pittoresken Dorf Hollenburg bei Krems: 72 km westlich von Wien (50 Min. Einfache Unterknfte in Hollenburg selbst& in den Nachbarorten Diverse gehobene Unterknfteim Umkreis von 10 km Eine sehr schne sptmittel-alterliche Kirche im Ort. official website and that any information you provide is encrypted As a direct result, Hemophilia became known as the Royal Disease. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. This can be achieved through similar analyses as those done by Ng et al. Counc. Blood type AB personality and behavior! Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis. Columns Mean CN show the log2 copy number change for the region in the first individual relative to the second in the comparison. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. Charge for additional parts/service if needed. Overall, and perhaps most importantly, the findings speak to the thorny relationship between biology and identity. Its also estimated that more than 99% of the Japanese are Rh+, so the familiar +/- seen after American blood types can usually be dispensed with. Four companion papers that relied on the rhesus sequence also appear in the same issue. While the system above is almost exclusively an east Asian trope, Western media does occasionally use blood types as metaphors for a characters personality, especially assigning Type O- (Universal Donor) to generous, selfless characters Only copy number regions that varied by at least a factor of two were used for gene copy number comparison between the species. PMC legacy view Not valid with other offers.No cash value. DNA Comparison Provides New Clues to Primate Biology. uva scott stadium parking. For other inquiries, please use this form. Now serving in Alberta. Ferguson B., Street S.L., Wright H., Pearson C., Jia Y., Thompson S.L., Allibone P., Dubay C.J., Spindel E., Norgren R.B., Jr. Brain-specific expression of an exogenous gene after i.v. Karolchik D., Hinrichs A.S., Furey T.S., Roskin K.M., Sugnet C.W., Haussler D., Kent W.J. Lets organize and know the personality of each blood type! MeSH Zimin A., Cornish A., Maudhoo M., Gibbs R., Zhang X., Pandey S., Meehan D., Wipfler K., Bosinger S., Johnson Z., Tharp G., Marcais G., Roberts M., Ferguson B., Fox H., Treangen T., Salzberg S., Yorke J., Robert Norgren. Bengtsson H., Wirapati P., Speed T.P. Resour. But an O-Neg person couldnt be given O-Positive, as their blood would clot. Worst traits: Jealous, arrogant. That tradition is waning, but it is, unfortunately, far from extinguished. Similar genomic rearrangements and regional inversions were observed in both Indian and Chinese rhesus macaques as compared to human with the exception of a single inversion block at the end of rhesus chromosome 10 and human chromosome 22 (Fig. The analysis also revealed a few instances in which whole families of genes were radically different in the rhesus, containing more copies of certain genes than in the chimp or human. They are ultimately ambiverts people who can display both introverted and extroverted tendencies. Multiplexed Simian Immunodeficiency Virus-Specific Paired RNA-Guided Cas9 Nickases Inactivate Proviral DNA. Who were the Watchers? Have you ever felt you were different ? and does affect your behavior, your mode, and your normal state of mind and you must seek help from a social worker with a master degree or a clinical National Library of Medicine Human chromosomes 5, 12, and X and their orthologous rhesus macaque chromosomes showed no microinversions or rearrangements in either the Indian or the Chinese rhesus macaque while human chromosome 19 also showed no rearrangement in the Chinese rhesus macaque. Schreiben Sie uns mittels des Kontaktformulars unten, schicken Sie uns eine Email an post@hochzeitsschloss-hollenburg.at, Obere Hollenburger Hauptstrae 14 All doubled region information, including accession numbers, genes, and counts in log base two, for all comparisons is summarized in Table3 and listed in detail in Supplementary File 4. Maybe idealistic about love The probe sequences and their corresponding coordinates in the UCSC Genome Browser's (https://genome.ucsc.edu/) [36] human genome (version hg19) were downloaded from the Affymetrix website (http://www.affymetrix.com/) and used to check that probe sequences aligned uniquely and perfectly to the rhesus macaque genomes. People with type A blood tend to be more sensitive and are more susceptible to stress. Human Genome Sequencing Center, Image source: J.M.Garg (Own work) [GFDL or CC-BY-SA-3.0-2.5-2.0-1.0], via Wikimedia Commons. Best traits: Sociable, adaptable Of the 221,268 markers mapped to both genomes, 105,248 mapped to 30,282 unique accession numbers and 14,337 unique annotated genes in human, and 23,378 markers mapped to 3731 unique accession numbers and 3704 genes in Chinese rhesus macaque. But i have many unexplained apparition and ghostly experience in my life. George H. W. Bush, Rick James, Britney Spears, Richard Nixon, and Adolf Hitler were type AB. Genetic differences between rhesus macaques from India and China have been characterized and can be used to determine an individual's country of origin [11], [12], [13], [14]. 2b). People with RH-negative blood group have certain characteristics that seem to be common among the majority. For national fleets, Grease Monkey is part of the FullSpeed Automotive network of over 700+ locations. If you are looking for a company with competitive pay, great benefits and a career path, apply today! RR018144-07), NIH grants RR005090 and RR025871 to D.G.S., and the UC Davis Henry A. Jastro Graduate Research Award to J.N. In addition, these studies examine the pattern of organ expression of the transgene in the rhesus monkey depending on whether the plasmid is under the influence of a widely expressed promoter, the SV40 promoter, or an ocular-specific promoter, the opsin promoter. The "melded assembly" used the fingerprint map and, at the very highest level (i.e., super-contig placement on the chromosomes), it referred to the human sequence. When comparing Chinese rhesus macaques to humans, the number of total copy number regions decreased to 305 and doubled regions to 32. The rhesus genomic DNA samples used for these studies were contributed by the California NPRC, Oregon NPRC, Southwest NPRC and Yerkes NPRC. They had children, many children. GUID:095A1D8A-0715-41A7-B0D1-5F63FAF01F16. Using human markers to investigate the rhesus macaque genomes has resulted in the identification of over 200,000 sites that are complementary to orthologous probes. For centuries, European royalty have been inflicted with Hemophilia or bleeders disease. Innocent and timid Wilke AB, Scaife S, Alphey L, Marrelli MT. It may be due to your DNA . When blood type is inherited from your parents, it is known that this factor element of the blood is the most consistent human or animal characteristic passed on to the offspring. They can be said as prudent people. Only customers who said they identified with a single racial or ethnic group were included. There's a link between racial identity and geography. Flying about in the sky ships and shooting fire and creating ear-shattering booms. Accessibility There are very few aberrations. *Where Manufacturers specifications allow. The only thing I s possible we are not alone. Results: In their analysis, scientists from 35 institutions compared this melded assembly to the reference sequence of the human genome, a newer unpublished draft sequence of the chimp genome, the sequence of more than a dozen other more distant species already in the public databases, the human HapMap, and the Human Gene Mutation Database that lists known human mutations that lead to genetic disease. Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer. Void where prohibited. Microglia and macrophages are essential for homeostatic maintenance and innate immune response in the brain. Federal government websites often end in .gov or .mil. Received 2015 Aug 24; Accepted 2015 Sep 12. The double region comparison for Indian rhesus-human resulted in 885 unique accession numbers and 407 unique genes in human and 96 unique accession numbers and genes in Indian rhesus macaque. Population genetics scientists from institutions including Harvard University analyzed DNA from thousands of Americans who described themselves as being part of a singular racial group. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11q21.3 region of chromosome 17.
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